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Or it can undergo P450 metabolism (most commonly CYP2E1 metabolism) to form NAPQI (N-Acetyl-p-benzoquinone imine), which can form a non-toxic product via glutathione conjugation (cysteine and mercapturic acid conjugates)

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Supplementary material The Supplementary Material for this article can be found online at: References 1 AkiyamaS.FukudaS.SteinbergJ

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The changes in the gut microbiota have the potential to influence immune system pathways and become key contributors to SLE pathology

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